For me, I can't wait to read: Pictures of You by Caroline Leavitt. Due out January 25, 2011 from Algonquin Books, amazon says this about the book:
Two women running away from their marriages collide on a foggy highway, killing one of them. The survivor is left to pick up the pieces, not only of her own life, but also must go back and deal with the devastated husband and fragile, asthmatic son the other woman left behind. Together, they try to solve the mystery of where April was running to, and why. By turns riveting and unsettling, Pictures of You looks at the choices women make-the roads they choose-to be loved.